解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Light-induced changes in the input resistance (Rin) of external, luminosity (i.e. H1) type horizontal cell (HC) perikarya were studied by the bridge-balance method in light-adapted and dark-adapted retinae of carp. Changes in input resistance (delta Rin) induced by short-(460 nm) and long-wavelength (674 nm) flashes, ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(96)01133-9
更新日期:1997-01-01 00:00:00
abstract::GABAergic characteristics of transcallosal activity of cat pyramidal tract neurons (PTNs) and non-PTNs (nPTNs) were studied with stressing on GABAB receptors. PTNs and nPTNs were further classified into group 1 (< 10 ms) and group 2 (> 10 ms) based on the latency upon transcallosal stimulation. However, mainly the res...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(96)01112-1
更新日期:1996-12-01 00:00:00
abstract::GABAergic neurons in the hippocampus proper are greatly diverse in their morphological and physiological features. In the present study we examined whether or not they are also diverse regarding the density of GABAergic input on their somata. GABAergic neurons were immunocytochemically identified with antibodies again...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(96)01102-9
更新日期:1996-10-01 00:00:00
abstract::Avian cochlear neurons of the nucleus magnocellularis (NMC) are known to encode temporal information of sound. The neuron generated only a single action potential at a stable timing even though suprathreshold currents of long duration (> 100 ms) was injected. The threshold for the action potential was -42 mV. In volta...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(96)01071-1
更新日期:1996-09-01 00:00:00
abstract::Adaptive changes in initial eye velocity of pursuit eye movement were examined in nine normal subjects using a target that moved in a multiple ramp fashion. Significant changes in initial eye velocity occurred rapidly after training in six of the subjects. The magnitude and direction of the induced changes were a func...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(96)01068-1
更新日期:1996-08-01 00:00:00
abstract::In the guinea-pig two subcortical structures have been shown to contain representations of auditory space, the deep layers of the superior colliculus (SC) and the external nucleus of the inferior colliculus (ICX). The following investigation was undertaken to determine if the ICX influences the development of the SC a...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(96)01060-7
更新日期:1996-07-01 00:00:00
abstract::The change in [Ca2+]i, in a retinal rod outer segment to flash and step stimuli was simulated. The present model included inward and outward calcium fluxes through cation channels and an Na-Ca-K exchanger, respectively, calcium buffers, and diffusion through the interdiskal space of cytoplasm and incisures. Under cont...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(96)01035-8
更新日期:1996-06-01 00:00:00
abstract::Using techniques of combining intracellular recording and intracellular staining with biocytin, 19 neurons have been sampled within or close to the CA1 pyramidal cell layer in hippocampal slices of the rat. All of these cells were physiologically characterized as non-pyramidal or interneurons based on their action pot...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(96)01024-3
更新日期:1996-05-01 00:00:00
abstract::Carbon monoxide (CO) is a gas that can permeate biological membranes and it has been suggested that the gas plays a signaling role in the brain by activating soluble guanylyl cyclase (sGC). CO is generated by heme oxygenase during the conversion of heme to biliverdin. In this study, we raised an antiserum against the ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(96)01018-8
更新日期:1996-03-01 00:00:00
abstract::Using Mayahara's method, the distribution of K(+)-dependent p-nitrophenylphosphatase activity was examined electron microscopically in the synaptic regions of the cerebral cortex of 10, 15 and 60-day-old Wistar rats. The enzyme achieved gradually its characteristic localization and uniform distribution. The main devel...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(95)01004-1
更新日期:1996-02-01 00:00:00
abstract::Many studies on long-term potentiation (LTP) in hippocampal region CA1 focus on receptor-mediated events that are often presumed to be linked to postsynaptic processes. Whereas it is now well-known that LTP consists of multiple components involving increases in postsynaptic responsiveness as well as enhanced presynapt...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(95)00986-8
更新日期:1996-01-01 00:00:00
abstract::Using a mouse Thy-1 allelic system (an AKR strain of Thy-1.1 was used as the host and a BALB/c strain of Thy-1.2 as the graft), characteristics of transplant-to-host axon projection and synapse formation of the olfactory bulb (OB) were studied in the hippocampal formation by immunohistochemical and ultrastructural exa...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(95)00979-5
更新日期:1995-12-01 00:00:00
abstract::The disposition of the facial vibrissae of the mouse is represented as a matrix-like array of cell aggregates in rows and columns at every station of the whisker-to-barrel pathway. In order to evaluate the role of each station in this pathway, lesions were made in the facial vibrissae of the mystacial group on P0-P3, ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(95)00969-Z
更新日期:1995-11-01 00:00:00
abstract::In previous studies we provided evidence for changes in prolactin (PRL) receptor levels in the male rat brain after continuously infusing morphine using subcutaneously implanted miniosmotic pumps. In this work we have studied the binding of PRL in the male rat brain following morphine administration by both subcutaneo...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(95)00953-1
更新日期:1995-10-01 00:00:00
abstract::In acute decerebrate cats, medial pontine reticular formation (mPRF) and the mesencephalic locomotor region (MLR) were stimulated and their stimulus effects upon 250 medullary reticulospinal neurons (RSNs) were studied. One hundred and twenty-six RSNs were mono- and disynaptically activated. From the response patterns...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:
更新日期:1995-08-01 00:00:00
abstract::Neuronal degeneration appears to be associated with changes in anti-ubiquitin immunoreactivity (UIR). To elucidate the relationship between the two events, we examined the time course of changes in UIR in pyramidal neurons of hippocampal organotypic cultures following exposure to an excitotoxin, N-methyl-D-aspartate (...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(95)00911-c
更新日期:1995-07-01 00:00:00
abstract::The distribution of neurofilament proteins and peripherin in the pituitary gland of the rat was studied with a panel of monoclonal and polyclonal antibodies recognizing different neurofilament subunits. In the posterior lobe, a dense plexus of neurofilament- and peripherin-immunoreactive fibers was seen. In the interm...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(95)00903-7
更新日期:1995-06-01 00:00:00
abstract::In the present study, the monoclonal antibody Alz-50 has been used to determine and compare the immunohistochemical localization of phosphorylated tau proteins in the developing and normal adult spinal cord. At all stages of fetal life Alz-50 fiber immunoreactivity was observed in the dorsal roots, in the dorsal and d...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(95)00897-2
更新日期:1995-05-01 00:00:00
abstract::Our purpose was to elucidate the functional roles of the laryngeal afferents in controlling vocalization. We investigated the effects of laryngeal deafferentation (sectioning the internal branch of the superior laryngeal nerve (ISLN)) on respiration and voice quality during electrically-induced vocalization in twelve ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(95)00877-v
更新日期:1995-03-01 00:00:00
abstract::The aim of the present study was to investigate whether increased concentrations of lactic acid and potassium chloride (KCl) in contralateral muscles can influence the sensitivity of primary and secondary muscle spindle afferents (MSAs) from ipsilateral extensor and flexor muscles. The experiments were performed on 7 ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(94)00864-c
更新日期:1995-02-01 00:00:00
abstract::We previously reported that the gamma gamma-isozyme of enolase, NSE), one of the glycolytic enzymes, promoted the survival of embryonic rat neocortical neurons in culture, but alpha alpha-isozyme (non-neuronal enolase) had no effect. In the present study, the neurotrophic effects of NSE on cultured mesencephalic and s...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(94)00849-b
更新日期:1995-01-01 00:00:00
abstract::Event-related potentials (ERPs) during an auditory discrimination task were recorded both on the surface and at a depth of the auditory cortex in rats. Ten-kilohertz rare and 5-kHz frequent tones were used with the probabilities of 0.2 and 0.8. Lever pressing within 2 s, following the onset of the rare tone, was rewar...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(94)90073-6
更新日期:1994-11-01 00:00:00
abstract::The occurrence of multiple proteoglycan species is a characteristic of the brain. The structural features of individually characterized proteoglycans in the brain are first introduced in brief, then some examples are shown that suggest a relationship between multiple proteoglycans and the many distinct cell types and ...
journal_title:Neuroscience research
pub_type: 杂志文章,评审
doi:10.1016/0168-0102(94)90088-4
更新日期:1994-09-01 00:00:00
abstract::A glial cell line designated as B2 was generated from primary cultures of oligodendrocytes/astrocytes isolated from an adult BALB/c mouse brain and maintained for over 1 year. Phenotypic characteristics of B2 cells were investigated by immunolabeling with cell type-specific markers for oligodendrocytes (O4 and galacto...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(94)90035-3
更新日期:1994-08-01 00:00:00
abstract::Using immunohistochemistry and retrograde transport techniques, this study demonstrates that serotonin (5-HT) cells in the dorsal tegmental gray of the pons at rostrocaudal from P1 to P6 levels are sources of bilateral serotonergic projections to the gigantocellular tegmental field of the medial pontine and medullary ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(94)90021-3
更新日期:1994-07-01 00:00:00
abstract::The cranial nerves and the brain fiber systems of the medaka (Oryzias latipes) fry are revealed by a whole-mount staining method. Newly hatched fry of an albino strain of the medaka were fixed, partially digested with trypsin, treated in 1% Triton X-100, and finally immunohistochemically stained using anti-neurofilame...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(94)90079-5
更新日期:1994-06-01 00:00:00
abstract::Changes in the features of responses of cortical taste neurons were studied in granular insular (GI) and dysgranular insular (DI) areas of urethane-anesthetized SD rats of four age groups (4-10, 14-20, 25-35 and > 90 days). Stimuli included four basic taste stimuli, 0.1 M NH4Cl, and the water extract of a food pellet,...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(94)90082-5
更新日期:1994-06-01 00:00:00
abstract::Distribution of the delta- and epsilon-subspecies of protein kinase C (PKC) in rat central nervous tissues was semiquantitated by an immunoblot analysis. The epsilon-subspecies, which is expressed predominantly in the brain, was abundant in hippocampus and cerebral cortex among rat brain areas, whereas the delta-subsp...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(94)90047-7
更新日期:1994-05-01 00:00:00
abstract::Immunohistochemical staining for GD3 in adult rat brain was carried out using mouse IgM anti-GD3 monoclonal antibody (DSG-1). Neuronal cells in the cerebral cortex, striatum, hippocampus and various nuclei of the thalamus were immunoreactive. In the cerebellum, Purkinje cells, granule cells and also basket cells were ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(94)90134-1
更新日期:1994-03-01 00:00:00
abstract::A group of brain acid-soluble proteins (BASPs) is preliminarily characterized. In some respects BASPs are similar to high mobility group (HMG) proteins, but in contrast to HMG, all BASPs are very acidic (pI 4.4-4.6) and show abnormal mobility during SDS-PAGE electrophoresis. BASP2-1 and BASP2-2 are identified as the t...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(94)90146-5
更新日期:1994-03-01 00:00:00
abstract::Using standard intracellular recording techniques 38 nonpyramidal cells or interneurons have been sampled in hippocampal slices of the rat. Among 38 physiologically identified interneurons, all 27 cells labeled with biocytin were morphologically demonstrated to be nonpyramidal and nongranule cells. The vast majority o...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(94)90013-2
更新日期:1994-02-01 00:00:00
abstract::The effects of 5-HT3-receptor-related agents on long-term potentiation (LTP) in the mossy fiber-CA3 system were studied in guinea pig hippocampal slices. 5-HT3 receptor agonists, 1-(m-chlorophenyl)-biguanide (mCPBG) and 2-methyl serotonin (2-Me-5-HT) significantly attenuated the magnitude of LTP of the population spik...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(94)90163-5
更新日期:1994-01-01 00:00:00
abstract::The effects of iontophoretically applied (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD), an agonist of metabotropic glutamate receptors, were examined in rat cerebellar Purkinje cells in vivo. Multibarrel electrodes were used for extracellular recordings of spontaneous single unit discharges and iontop...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(93)90057-w
更新日期:1993-12-01 00:00:00
abstract::The effects of acupuncture-like stimulation of the various segmental areas on gastric motility were examined in anesthetized rats. An acupuncture needle (diameter 340 microns) was inserted into the skin and underlying muscles at a depth of 4-5 mm and was twisted right and left once every second for 60 s. Gastric motil...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(93)90105-y
更新日期:1993-10-01 00:00:00
abstract::Hippocalcin is a recently identified Ca(2+)-binding protein with three EF-hand structures, dominantly expressed in the hippocampal pyramidal layer. The complete amino acid sequence of hippocalcin deduced from the cDNA is composed of 195 residues, has a calculated molecular mass of 22,574 daltons, and has a striking se...
journal_title:Neuroscience research
pub_type: 杂志文章,评审
doi:10.1016/0168-0102(93)90112-4
更新日期:1993-09-01 00:00:00
abstract::The A5 is an unique membrane protein that is expressed in the neurons of the visual system and general somatic sensory system of Xenopus laevis. We cultured retinal explants or trigeminal ganglion neurons on the monolayers of A5-expressing line cells obtained by transfection with the cDNA, and found that the A5-expres...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(93)90092-5
更新日期:1993-07-01 00:00:00
abstract::Electromyograms were recorded from the intralaryngeal muscles (the posterior cricoarytenoid (PCA) and thyroarytenoid (TA) muscles) and the ventilatory muscles (the diaphragm (DA) and abdominal (RA) muscle) during electrically induced vocalization in precollicular postmammillary decerebrate cats. Electrical stimulation...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(93)90032-l
更新日期:1993-06-01 00:00:00
abstract::The responses of slice-cultured Purkinje cells to trans-DL-1-amino-1,3-cyclopentanedicarboxylic acid (t-ACPD) were examined by intracellular recording techniques and fura-2 microfluorometry. Bath-application of t-ACPD (100 microM, 30 s), a selective agonist of metabotropic glutamate receptors (mGluRs), to Purkinje cel...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(93)90125-a
更新日期:1993-03-01 00:00:00
abstract::Changes in voltage-dependent Na+ (INa) and Ca2+ currents (ICa) were investigated in PC12 cells cultured without or with either nerve growth factor (NGF) or 8-Br-cAMP for 10 days. Current recordings were made in the whole-cell mode by using the conventional patch-clamp technique under voltage-clamp conditions. Membrane...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(93)90081-z
更新日期:1993-02-01 00:00:00
abstract::In the vertebrate nervous system, glutamate (Glu) receptors are generally known to cause depolarizing responses. We report here a novel type of Glu response in Purkinje neurons of mouse cerebellar slices, namely glutamate-induced hyperpolarization (GH). This response is not due to activation of inhibitory interneurons...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(92)90047-g
更新日期:1992-12-01 00:00:00